Since the infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in China during December 2019, the coronavirus disease 2019 (COVID-19) has spread on a global scale, causing the World Health Organization (WHO) to issue a warning. While novel vaccines and drugs that target SARS-CoV-2 are under development, this review provides information on therapeutics which are under clinical trials or are proposed to antagonize SARS-CoV-2. Based on the information gained from the responses to other RNA coronaviruses, including the strains that cause severe acute respiratory syndrome (SARS)-coronaviruses and Middle East respiratory syndrome (MERS), drug repurposing might be a viable strategy. Since several antiviral therapies can inhibit viral replication cycles or relieve symptoms, mechanisms unique to RNA viruses will be important for the clinical development of antivirals against SARS-CoV-2. Given that several currently marketed drugs may be efficient therapeutic agents for severe COVID-19 cases, they may be beneficial for future viral pandemics and other infections caused by RNA viruses when standard treatments are unavailable.
Keywords: COVID-19; coronavirus; infection; drug discovery; drug repositioning
BT731 Assignment 2 Solution and Discussion
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BT731 – Modern Biotechnology: Principles and Applications
Assignment No. 2
Fall 2019
Due Date: January 23, 2020
Audio Presentation
“Please prepare audio ppts slides of the review article “Potential of CRISPR-Cas9 for treating genetic disorders”, already submitted as Assignment No. 1’ through power point”
General instructions
• Total time of audio presentation should be 10 minutes.
• Total ten slides should be prepared.
• This assignment will be carrying 10 marks.
• Ten slides (containing text) and recording on each slide “audio ppts file” should be uploaded on LMS not later than 23rd January, 2020.Instructions for audio recording through power point.
• Open power point
• Create “new slide”
• Go to “insert” in tool bar
• Go to “Audio” option in media (extreme right option in power point tool bar)
• Start recording on each slideOutcomes:
This assignment will help you to develop presentation skills and strengthen you more to understand your already submitted review article.


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